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Is EPO used in cancer treatment? Only 4 years later, the US Food and Drug Administration (FDA) approved the first commercially available recombinant human erythropoietin (rHuEPO), epoetin alfa, for the treatment of anemia associated with chronic kidney disease (CKD) (6).
What class of drug is epoetin alfa? Epoetin alfa belongs to a class of drugs called colony-stimulating factors because of their ability to stimulate cells in the bone marrow to multiply and form colonies of identical cells.
Why is my hemoglobin low? Low hemoglobin levels usually indicate that a person has anemia. Vitamin-deficiency anemia happens when there are low levels of nutrients, such as vitamin B12 or folic acid (also called folate), in the diet. These anemias change the shape of the red blood cells, which makes them less effective.
Does erythropoietin contain blood? Red blood cells are produced in the bone marrow (the spongy tissue inside the bone). In order to make red blood cells, the body maintains an adequate supply of erythropoietin (EPO), a hormone that is produced by the kidney. Hemoglobin is the protein in red blood cells that helps blood carry oxygen throughout the body.
What level of ferritin is considered anemic? Lower than normal hemoglobin levels indicate anemia. The normal hemoglobin range is generally defined as 13.5 to 17.5 grams (g) of hemoglobin per deciliter (dL) of blood for men and 12.0 to 15.5 g/dL for women. The normal ranges for children vary depending on the child's age and sex. Ferritin.
What is the best form of iron to take for anemia? Iron is found in the diet in two forms —heme iron, which is well absorbed, and nonheme iron, which is poorly absorbed. The best dietary source of absorbable (heme) iron is lean red meat.
How long does it take to feel better with anemia? Most people start to feel better within a few days of beginning treatment. Even though you feel better, you will need to keep taking the pills for several months to build up your iron stores. Sometimes it takes up to 6 months of treatment with iron supplements before iron levels return to normal.
Does anemia ever go away? Blood transfusions and a bone marrow transplant are treatment options for both types of anemia. The most common form of the disorder is iron deficiency anemia. "If you're losing blood from somewhere, once you address that the anemia will go away fairly quickly," said Paranjape.
What is the survival rate of aplastic anemia? The case fatality rate of severe aplastic anemia is high although treatment, whether by allogeneic stem-cell transplantation or immunosuppression, has dramatically improved the prognosis over the last 25 years, and more than 75% of patients can now be expected to have long term survival with either therapy.
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